The Effects of Exercise Before Doxorubicin Chemotherapy on Cardiac Function

Principal Investigators:

Kristin Campbell
Karen Gelmon (Medical Oncologist, BC Cancer Agency)

Student Project Leader:

Amy Kirkham, PhD Candidate


Women with breast cancer may choose to exercise on their own or in close proximity to receipt of their chemotherapy treatments. This study will investigate the effect of a single bout of aerobic exercise 24 hours prior to chemotherapy treatments. Participants scheduled to receive chemotherapy for breast cancer will be randomized to exercise or no exercise 24 hours prior to every chemotherapy treatment. The effect on cardiac function will be compared between groups noninvasively by echocardiography and a venous blood draw at baseline before chemotherapy, after the first treatment and at the end of chemotherapy.

You are eligible to participate in this study if you are:

  • Diagnosed with early breast cancer (stage I-III)
  • Scheduled and not yet started a chemotherapy protocol including adriamycin (a.k.a doxorubicin)
  • Age 18 or older
For more information and to determine your eligibility, please contact:
Amy Kirkham, or 604-827-1914

This project is funded by the Anita Cochrane Memorial Endowment Fund Award from the BC Cancer Foundation.

Amy Kirkham is supported by a Canada Graduate Scholarship Doctoral Award from the Canadian Institute of Health Research.